Heavy charged particle therapy.
نویسندگان
چکیده
منابع مشابه
Tumor Therapy with Heavy Charged Particles
The inverse depth dose profile i.e. the increase of the dose with penetration depth make heavy charged particles like protons and heavy ions an ideal tool for the radiotherapy of deep-seated tumors. For carbon ions this good dose profile is potentiated by an additional increase in the relative biological effectiveness (RBE) towards the end of the particle range. The physical and biological basi...
متن کاملCharged Particle Therapy with Mini-Segmented Beams
One of the fundamental attributes of proton therapy and carbon ion therapy is the ability of these charged particles to spare tissue distal to the targeted tumor. This significantly reduces normal tissue toxicity and has the potential to translate to a wider therapeutic index. Although, in general, particle therapy also reduces dose to the proximal tissues, particularly in the vicinity of the t...
متن کاملEvaluation of the dose variation for prostate heavy charged particle therapy using four-dimensional computed tomography
We quantified dose variation effects due to respiratory-induced intrafractional motion in conventional carbon-ion prostate treatment by using four-dimensional computed tomography (4DCT). 4DCT scans of 20 patients were acquired under free-breathing conditions using a 256 multi-slice CT scanner. The clinical target volume (CTV) was defined as the prostate and the seminal vesicle. Two types of pla...
متن کاملPromise and pitfalls of heavy-particle therapy.
Proton beam therapy, the most common form of heavy-particle radiation therapy, is not a new invention, but it has gained considerable public attention because of the high cost of installing and operating the rapidly increasing number of treatment centers. This article reviews the physical properties of proton beam therapy and focuses on the up-to-date clinical evidence comparing proton beam the...
متن کاملKill-painting of hypoxic tumours in charged particle therapy
Solid tumours often present regions with severe oxygen deprivation (hypoxia), which are resistant to both chemotherapy and radiotherapy. Increased radiosensitivity as a function of the oxygen concentration is well described for X-rays. It has also been demonstrated that radioresistance in anoxia is reduced using high-LET radiation rather than conventional X-rays. However, the dependence of the ...
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ژورنال
عنوان ژورنال: Japanese jornal of Head and Neck Cancer
سال: 1995
ISSN: 1883-9878,0911-4335
DOI: 10.5981/jjhnc1974.21.591